Best Multivitamins of 2025: Evidence-Based Reviews
We analyzed dozens of multivitamins to bring you the top options based on ingredient quality, bioavailability, third-party testing, and value. All recommendations are backed by research and transparent sourcing.
Research Methodology: Products were evaluated based on ingredient forms, dosing, third-party testing, manufacturer reputation, and customer reviews. We prioritize bioavailable forms like methylfolate over synthetic folic acid.
Quick Comparison
| Rank | Product | Rating | Price | Best For | Action |
|---|---|---|---|---|---|
| #1 | Garden of Life Vitamin Code Men/Women | ★4.6/5 | $35-40 | Those seeking whole food-based nutrition with probiotics | View on Amazon |
| #2 | Thorne Basic Nutrients 2/Day | ★4.7/5 | $30-35 | Athletes and those wanting pharmaceutical-grade quality | View on Amazon |
| #3 | Pure Encapsulations O.N.E. Multivitamin | ★4.5/5 | $28-32 | People with sensitivities seeking a simple once-daily option | View on Amazon |
| #4 | Optimum Nutrition Opti-Men/Opti-Women | ★4.4/5 | $20-25 | Active individuals and athletes on a budget | View on Amazon |
| #5 | MegaFood One Daily | ★4.3/5 | $25-30 | Those with sensitive stomachs seeking food-based vitamins | View on Amazon |
Detailed Reviews
#1
Garden of Life Vitamin Code Men/Women
★4.6/5 Rating$35-40
Best For: Those seeking whole food-based nutrition with probiotics
Pros
- • Whole food-based ingredients
- • Includes probiotics and enzymes
- • Raw, third-party tested
- • Gender-specific formulas available
Cons
- • Large capsule size
- • Higher price point
- • Requires multiple capsules per serving
Key Ingredients
B-ComplexVitamin D3FolateLive ProbioticsRaw Enzymes
#2
Thorne Basic Nutrients 2/Day
★4.7/5 Rating$30-35
Best For: Athletes and those wanting pharmaceutical-grade quality
Pros
- • NSF Certified for Sport
- • High-quality bioavailable forms
- • No unnecessary additives
- • Trusted by healthcare professionals
Cons
- • Premium pricing
- • Only 2 capsules daily (may limit dosing flexibility)
- • Limited trace minerals
Key Ingredients
MethylfolateActive B12Vitamin D3Mixed Tocopherols
#3
Pure Encapsulations O.N.E. Multivitamin
★4.5/5 Rating$28-32
Best For: People with sensitivities seeking a simple once-daily option
Pros
- • Once-daily convenience
- • Hypoallergenic formula
- • High-potency B vitamins
- • No artificial additives
Cons
- • Lower mineral content
- • No iron (which some may need)
- • Single capsule limits customization
Key Ingredients
Metafolin L-5-MTHFB12 as methylcobalaminVitamin D3Lutein
#4
Optimum Nutrition Opti-Men/Opti-Women
★4.4/5 Rating$20-25
Best For: Active individuals and athletes on a budget
Pros
- • Excellent value for money
- • Comprehensive amino acid blend
- • High B-vitamin content
- • Gender-specific formulations
Cons
- • Very high in some vitamins (may exceed needs)
- • Large tablet size
- • Contains some synthetic forms
Key Ingredients
High B-ComplexAmino AcidsBotanical BlendEnzymes
#5
MegaFood One Daily
★4.3/5 Rating$25-30
Best For: Those with sensitive stomachs seeking food-based vitamins
Pros
- • Made with real food
- • Can be taken on empty stomach
- • Non-GMO and gluten-free
- • Gentle on digestion
Cons
- • Lower potency than some competitors
- • Minimal mineral content
- • More expensive per nutrient
Key Ingredients
FoodState NutrientsFolateB12Vitamin D3
How to Choose the Right Multivitamin
Key Factors to Consider
- Bioavailable Forms: Look for methylfolate instead of folic acid, methylcobalamin instead of cyanocobalamin, and chelated minerals for better absorption.
- Third-Party Testing: Choose products certified by NSF, USP, or Labdoor for quality assurance.
- Gender and Age: Some formulas are optimized for men, women, or specific age groups with tailored nutrient ratios.
- Dietary Restrictions: Check for allergens, non-GMO, vegan, or gluten-free certifications if needed.
- Dosing Flexibility: Multi-capsule servings allow you to adjust intake based on diet and needs.
What to Avoid
- Synthetic dyes and unnecessary fillers
- Mega-doses that far exceed daily needs (unless recommended by a healthcare provider)
- Proprietary blends that hide ingredient amounts
- Brands without third-party testing or transparency
Disclaimer: As an Amazon Associate, we earn from qualifying purchases. The information provided is for educational purposes only and is not medical advice. Consult your healthcare provider before starting any supplement regimen, especially if you have health conditions or take medications.